Monofixation syndrome (blind spot syndrome; primary monofixation)

General: No hereditary factor; uncommon.

Ocular: Deviation of eight prism diopters or less by simultaneous prism and cover test; central scotoma; stereopsis; good fusional vergences found in patients with congenital esotropia; unilateral syphilitic optic perineuritis (rare); congenital esotropia (inherited in a multifactorial fashion).

Clinical: Syphilis (rare).

Bolet RV. Development of mono fixation syndrome in congenital esotropia. J Pediatr Ophthalmol Strabismus 1981; 18:49-51.

Fletcher WA, et al. Acute Idiopathic blind spot enlargement. Arch Ophthalmol 1988; 106:44-49.

Hahn E, et al. Factors associated with binocular single vision in microtropia/monofixation syndrome. Can J Ophthalmol 1991; 26:12-l7.

McBurney J, Rosenberg M. Unilateral syphilitic optic perineuritis presenting as the big blind spot syndrome. J Clin Neuro-Ophthalmol 1987; 7:167.

Morris RJ, et al. Fusion after surgical alignment of long-standing strabismus in adults. Ophthalmology 1993; 100: 135-l38.

Parks MM. The monofixation syndrome. Trans Am Ophthalmol Soc 1969; 67:809-855.

Scott MJ, et al. Prevalence of primary mono fixation syndrome in parents of children with congenital esotropia. J Pediatr Ophthalmol Strabismus 1994; 31:298-301.