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Diseases

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Vaccinia


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General: Laboratory virus used for vaccination against smallpox.

Ocular: Pustules of lids; edema of lids; conjunctivitis; orbital cellulitis; keratitis; pannus; corneal perforation; iridocyclitis; central serous retinopathy; perivasculitis; pseudoretinitis pigmentosa; ocular palsies papillitis; optic atrophy.

Clinical: Vesicles; pustules; erythema; fever; malaise; axillary lymphadenopathy; necrosis of skin; vaccinia gangrenosa; encephalomyelitis; drowsiness; vomiting; coma; death.

Goldstein JA, et al. Smallpox vaccination reactions, prophylaxis, and therapy of complications. Pediatrics 1975; 55: 342-347.

Harley RD, ed. Pediatric Ophthalmology. 4th ed. Philadelphia: WB Saunders, 1998.

Lee SF, et al. Vaccinia keratouveitis manifesting as a masquerade syndrome. Am J Ophthalmol 1994; 117: 480-487.

Fraunfelder FT, Roy FH. Current Ocular Therapy. 5th ed. Philadelphia: WB Saunders, 1995: 105.

Pettit TH. The poxviruses: vaccinia and variola. Int Ophthalmol Clin 1975; 15:203-210.




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