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Diseases

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Rheumatic fever


Rheumatic Fever

General: Streptococcal infection; mechanisms may invo 151b18b lve immune cross-reactivity between bacterial heat shock proteins and similar proteins in normal human tissues.

Ocular: Lid edema; characteristic arborizations of conjunctiva; subconjunctival hemorrhages; episcleritis; scleritis; tenonitis; uveitis; retinal detachment; central retinal artery occlusion; optic neuritis.

Clinical: Hematuria; proteinuria; proliferative glomerulonephritis; microembolization; calcific emboli; sore throat; fever; chorea; erythema marginatum; disseminated encephalomyelitis.

Collins JF. Handbook of Clinical Ophthalmology. New York: Masson, 1982.

Harley RD, ed. Pediatric Ophthalmology, 4th ed. Philadelphia: WB Saunders, 1998.

Munn R, et al. Acute encephalomyelitis: extending the neurological manifestations of acute rheumatic fever? Neuro-pediatrics 1992; 23:196-l98.

Pantel GA, et al. Monocular blindness secondary to calcific embolization: an unusual presentation of rheumatic mitral valvular disease. Chest 1976; 69:555-556.

Smiley JD, Hoffman WL. The role of infections in the rheumatic diseases: molecular mimicry between bacterial and human stress proteins? Am J Med Sci 1991; 301:138-l49.




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