Reticulum cell sarcoma (non-hodgkin lymphoma)

General: Autosomal recessive; large 131f58b -cell lymphoma with chronic inflammation with a predominance of cells in vitreous cavity; average age at time of diagnosis is 60 years; female to male ratio is approximately 2: 1; 80% bilateral (frequently asymmetrical).

Ocular: Chronic uveitis; chorioretinal lesions; mycosis fungoides; necrosis of orbital tissues; phthisis bulbi; endophthalmos; exophthalmos; exudative retinal detachment; iris neovascularization; glaucoma; branch retinal vein occlusion; macular edema; optic neuropathy; vitreous hemorrhage; partial cranial nerve III palsy; multiple retinal pigment epithelium masses.

Clinical: Lymphocytic hyperplasia; fever; anemia; thrombocytopenia; liver and spleen enlargement; associated with immune dysfunction states, such as acquired immunodeficiency syndrome, or following transtation.

Duane TD. Clinical Ophthalmology. Philadelphia: JB Lippincott, 1987.

Lewis H, Schachat AP. Non-Hodgkins ('reticulum cell') lymphoma. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology, vol. II. Philadelphia: WB Saunders, 1994:893.

Miller NR. Walsh and Hoyt's Clinical Neuro-Ophthalmology, 4th ed. Baltimore: Williams & Wilkins, 1987.