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Jones syndrome (cherubism; mandibular cystic dysplasia)


Jones Syndrome (Cherubism; Mandibular Cystic Dysplasia)

General: Etiology unknown; both sexes affected; present at birth.

Ocular: White line beneath the iris on sclera; hypertelorism; optic atrophy.

Clinical: Rounded cheeks; jaw fullness; submandibular region swelling; narrow, V-shaped palate.

Al-Gazali LI, et al. Cherubism, optic atrophy and short stature. Clin Dysmorphol 1993; 2:140-l41.

Font RL, Blanco G, Soparkar CN, et al. Giant cell reparative granuloma of the orbit associated with cherubism. Ophthalmology 2003; 110: 1846-l849.

Jones WA. Familial multilocular cystic disease of the jaw. Am J Cancer 1933; 17:946-950.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.




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