Garcin Syndrome (Half-Base Syndrome; Schmincke Tumor-Unilateral Cranial Paralysis)
General: Causes include tumors of nasopharynx, rapidly progressing growth of a sarcoma of base of skull, meningiti 757e45h s, and cranial polyneuritis; cranial nerves VIII to XII are most frequently involved.
Ocular: Ptosis (unilateral); unilateral external ophthalmoplegia; papilledema.
Clinical: Difficulties in swallowing; impairment of speech; hearing defect; respiratory difficulties; sensory disturbances; hoarseness.
Bruce JN, Fetell MR. Tumors of the skull and cranial nerves. In: Rowland LP, ed. Merritts Textbook of Neurology, 9th ed. Baltimore: Williams & Wilkins, 1995:320-329.
Chakrabarti AK. Nasopharyngeal carcinoma with multiple cranial nerve palsies. Practitioner 1974; 212: 103.
Garcin R. Le Syndrome Paralytique Unilateral Global des Nerfs Craniens. Doctoral Thesis, University of Paris, 1927.
Geeraets WJ. Ocular Syndromes. 3rd ed. Philadelphia: Lea & Febiger, 1976.
Hochberg F, Pruitt A. Neoplastic diseases of the central nervous system: tumors of the skull base. In: Isselbacher KJ, et al., eds. Harrisons Principles of Internal Medicine, 13th ed. New York: McGraw-Hill, 1994:2267.
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