Diphtheria   371

General: Acute infectious disease caused by Corynebacterium diphtheriae; severity is dependent upon the amount of exotoxin absorbed prior to initiation of specific therapy.

Ocular: Conjunctivitis; xerophthalmia; keratitis; corneal ulcer; blepharitis; cellulitis of lid; meibomianitis; ptosis; dacryocystitis; cataract; central retinal artery occlusion; optic neuritis; accommodative spasm or paralysis; convergence paralysis; divergence paralysis; paralysis of third, fourth, or sixth nerve; paralysis of accommodation (in children); ocular motor nerve paresis; choroiditis; cranial neuropathies involving the trigeminal, vagus, and hypoglossal cranial nerves; myocarditis.

Clinical: Local inflammatory lesion, with effect on heart, kidneys, and nervous system.

Collins JE Handbook of Clinical Ophthalmology. New York: Masson, 1982.

Duke-Elder S, ed. System of Ophthalmology, vol. XV. St. Louis: CV Mosby, 1976:46.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Holmes RK. Diphtheria. In: Isselbacher KJ, et al., eds. Harrison’s Principles of Internal Medicine, 13th ed. New York: McGraw-Hill, 1994:623-627.

Miller NR, ed. Walsh and Hoyt’s Clinical Neuro-Ophthalmology, vol. 5, part 1, 4th ed. Baltimore: Williams & Wilkins, 1995.