Addison syndrome (addison disease; idiopathic hypoparathyroidism; adrenal cortical insufficiency; moniliasis-idiopathic hypoparathyroidism)

General: Familial occurrence; association with moniliasis; onset during end of first and beginning of second decade of life; atrophy of adrenal cortex; prognosis for life is poor, with death in adrenal crisis.

Ocular: Ptosis; blepharitis; blepharospasm; keratoconjunctivitis with extreme photophobia; corneal ulcers; episcleritis; keratitic moniliasis; cataracts; papilledema.

Clinical: Moniliasis; tetany; progressive weakness; anorexia; progressive skin pigmentation; dry skin; brittle fingernails and toenails; sparse pubic and axillary hair or total alopecia; impotence.

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Collins JF. Handbook of Clinical Ophthalmology. New York: Masson, 1982:229.

Gass JD. The syndrome of keratoconjunctivitis, superficial moniliasis, idiopathic hypoparathyroidism and Addison's disease. Am J Ophthalmol 1962;

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.

Williams GH, Dluhy RG. Diseases of the adrenal cortex. In: Isselbacher KJ, et al., eds. Harrisons Principles of Internal Medicine, 13th ed. New York: McGraw-Hill, 1994:1953-l975.